British Air Force Typhoon jets have joined forces with French aircraft in a combined operation against an subterranean weapons facility in Syrian territory operated by the IS group, as stated by the UK's MoD.
The facility, identified by reconnaissance, was thought to be storing arms and explosives, the statement said, and was situated in hills just north of the historic site of Palmyra in Syria's central region.
"The RAF jets utilized precision-guided Paveway IV munitions to strike a number of access tunnels leading to the depot... preliminary assessments indicate the target was engaged successfully," officials stated.
There was no evidence of any civilian casualties in the strike on Saturday evening and all the aircraft returned to base without incident, the ministry further stated.
The British jets were assisted by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as ISIS - imposed extremist governance over parts of both Syria and Iraq before its territorial defeat in 2019.
"This strike demonstrates our UK leadership, and determination to operate in unison with our allies, to eliminate any resurgence of IS and their violent and radical beliefs in the region," the British Defence Secretary John Healey said.
RAF aircraft have carried out patrols over Syrian airspace to "prevent any efforts to regroup" of Islamic State subsequent to its defeat at the Baghuz confrontation in 2019, the ministry said.
"I must thank the personnel of British forces who took part in this strike for their professionalism and their courage," Healey added. "Including them were thousands of UK service members deployed over the festive period. This action, to remove dangerous terrorists who pose a risk to our way of life, demonstrates how our armed forces are always on standby, continuously, keeping Britain secure at home and powerful internationally."
In December, the United States armed forces carried out what it described as a "major assault" targeting IS targets in the country, after an attack resulted in the deaths of two American soldiers and a local interpreter in the Palmyra area.
The U.N. estimates Islamic State still has an estimated 5,000 to 7,000 militants in Syria and Iraq.